$27.00 [kindle download: $22.00]
SCALPEL
The HIV/AIDS novel
by N. A. AKAMIKE
Jaguda is a maverick scientist who sets out to rescue a failing giant pharmaceutical company. He attempts to develop new antiretroviral ARV drugs for HIV that will be revolutionary.
First, he reviews the existing pipeline of drugs in order to redesign them. Second, he shifts his company's research and development from stem cell research to conventional medicinal chemistry approaches. The problems become complicated and magnified. The international implication of the pandemic is imminent. The company's board of directors is nervous.
Although he is married, he falls in love with his secretary, who incidentally does not love him. He persuades her to go on a secret romantic rendezvous in Paris on the corporate account. Following a series of corporate espionage by internal affairs, his illicit affair with his secretary is exposed. His wife later finds out. The turbulence of
marital infidelity follows. His ambitious and desperate attempt to dominate the pharmaceutical industry leads him toward a buy-out plot of a smaller biotech pharma that has discovered a revolutionary compound for the global eradication of AIDS. The discovery is made after the biotech pharma investigates the HIV epidemic in the Democratic Republic
of Congo, DRC, in the Sub-Sahara Africa. The intriguing undercover involvement of
hired detectives and his office romance, compounded by unhappy board members and stakeholders laced together, culminates in a series of adverse domino effect. Does he survive?
About the Author :
N. A. AKAMIKE is a research scientist in pharmaceutical
sciences and industrial chemistry, a recipient of the sigma xi
award, the inventor of four patents related to cancer, coauthor
of several scientific publications in the area of HIV/AIDS, and
the author of SOFT TISSUE, a novel on breast cancer.
Cover Design by Nicole Kuhn
ISBN# 978-1-4349-6547-9
RED LEAD PRESS
701 SMITHFIELD STREET • PITTSBURGH, PA 15222
AVAILABLE AT: AMAZON.COM
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Soft Tissue by N. A. Akamike,
ISBN #: 978-0-8059-8446-0
$16.00 [kindle books download - $11.00]
Soft Tissue: The Unsolved Mystery, Breast Cancer” is a fictitious story that blends aspects of medical and sociological drama creating a contemporary, thrilling, fast paced and engaging novel. The story begins with Roxy Adams striking a friendship with Elaine, Ifeoma, and Beatrice during the Chicago’s mayoral election. Their friendship culminated in a vacation to Egypt. Roxy, the daughter of an industrialist father whose wife has a genetic link to cancer, fell in love with James Ugo, a scientist, en route to Egypt. A romantic relationship developed between James and Roxy that continued after the end of the Egyptian vacation. Her relationship with James headed towards marriage. The interests and professional ties of Roxy, an attorney, and her friends provided a forum for an extensive discussion of breast cancer. The scientist and medical doctors elaborated on most aspects of the cancer, possible risk factors, including oral contraceptives and hormone based therapies. When Roxy was suddenly diagnosed with breast cancer, her curiosity about the origin and progress of breast cancer expanded the conversation to include considerations of stem cell research and genetic influences. The diagnosis exposed the fragility of the love between Roxy and James. The emotional turmoil as a result of the diagnosis compounded by potential infidelity by James caused Roxy to have an accident. On the other hand, Denise who suffered a stroke as a consequence of HRT use faced uncertainty in her proposed marriage to her long term fiancé, Charles.
RED LEAD PRESS
701 SMITHFIELD STREET • PITTSBURGH, PA 15222
AVAILABLE AT: AMAZON.COM
--------------------- THE FOLLOWING BOOKS ARE COMING SOON: 1.AMIDES AND ESTERS IN DRUG DISCOVERY BY EMEKA AKAMIKE This manuscript explores the role of amides and esters in drug discovery 2. ANTIMALARIA DRUGS PATTERN IN DRUG DISCOVERY Part one BY EMEKA AKAMIKE A statistical review of anti-malaria drugs This manuscript is a review of the evolution of malaria and anti-malaria drugs, a statistical and chemical analysis of anti-malarial drugs to identify patterns and violations of Lipsinki rule of five (Ro5). It proposes the next generation of anti-malarial drugs. The calculations for statistical analysis were done for parameters such as cLog P, parachor, polarizability, molar refractivity, druglikeness, etc. It reviews the control of malaria that includes biochemical, chemical, structural and pattern analysis of insecticides. 3. BIO-ENERGY COMPOUNDS PATTERNS-Part 1 BY EMEKA AKAMIKE ATP AND ATP DERIVATIVES/VITAMINS This manuscript is a computer-aided analysis of a whole array of energy sources in the human body and their bioactivity/molecular properties patterns. The relationship of antioxidants to longevity, various diseases such as cardiovascular disease, arthritis, COPD, Parkinson’s disease, and cystic acne is explored including their effect on physical exercise. Fatty acids antioxidant properties are compared to the hypothetical substituted derivatives to expose a unique pattern. The effect of antioxidants on free radicals is illustrated with the drug edaravone, a free radical scavenger, on Parkinson’s disease. Free radical induced oxidative stress is involved in the mechanisms of cell death in Parkinson’s disease, and edaravone exerts a neuroprotective effects on Parkinson disease. The antioxidant properties of food additives are reviewed. Compounds such as anthocyanins, glutathione, uric acid, ubiquinones, melatonin, caffeine and the coenzymes A & Q series display characteristic pattern including blood thinners. 4. DRUG PATTERNS IN DRUG DISCOVERY –Part 1 BY EMEKA A. AKAMIKE October 24 2012 This manuscript explores the statistical relationships between the physicochemical parameters (clog P, parachor, molecular weight, molar volume, polarizability, molar refractivity, PSA, log BB, druglikeness, and calculated formula weight, CFW), and bioactivity data in the five therapeutic areas (anticholesterol drugs (STATINS), antiretroviral (ARV), central nervous system (CNS), steroids, and mustards. Finally, it predicts the next generation of nitrogen mustards. A statistical evaluation
